DelveInsight’s, “Pemphigus Vulgaris Pipeline Insight, 2025” report provides comprehensive insights about 3+ companies and 3+ pipeline drugs in Pemphigus Vulgaris pipeline landscape. It covers the Pemphigus Vulgaris pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Pemphigus Vulgaris pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
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Key Takeaways from the Pemphigus Vulgaris Pipeline Report
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Pemphigus Vulgaris Emerging Drugs Profile
CABA-201 is a 4-1BB-containing fully human CD19-CAR T cell investigational therapy for patients with autoimmune diseases where B cells contribute to the initiation and/or maintenance of disease. Following a one-time infusion, CABA-201 is designed to transiently and completely deplete all CD19-positive cells. This approach has the potential to reset the immune system and result in compelling clinical responses without chronic therapy requirements in patients. Cabaletta is currently evaluating CABA-201 in the RESET™ (REstoring SElf-Tolerance) clinical development program which includes multiple disease-specific, company-sponsored clinical trials across growing portfolios of autoimmune diseases in a broad range of therapeutic areas, including rheumatology, neurology and dermatology. Currently, the drug is in Phase I/II stage of its development for the treatment of Pemphigus Vulgaris.
AlloNK is an allogeneic, off-the-shelf, cryopreserved NK cell therapy candidate designed to enhance the ADCC effect of mAbs to drive B-cell depletion. AlloNK, as a non-genetically modified, non-targeted NK cell, is designed to utilize a mAb or NK engager for targeting, and therefore can be used in different combinations against different therapeutic targets. AlloNK is currently in clinical trials for treatment of systemic lupus erythematosus (SLE) for patients with or without lupus nephritis and in a basket investigator-initiated trial (IIT) in multiple autoimmune indications. In addition, AlloNK is being evaluated for the treatment of non-Hodgkin lymphoma, as well as in combination with Affimed’s innate cell engager acimtamig for the treatment of patients with relapsed/refractory CD30-positive lymphomas. Currently, the drug is in Phase I stage of its development for the treatment of Pemphigus Vulgaris.
The Pemphigus Vulgaris Pipeline Report Provides Insights into
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Pemphigus Vulgaris Companies
Cabaletta Bio, Artiva Biotherapeutics Inc., Serpin Pharma and others.
Pemphigus Vulgaris pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Pemphigus Vulgaris Products have been categorized under various Molecule types such as
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Scope of the Pemphigus Vulgaris Pipeline Report
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